Sample News feed http://www.mip-dili.eu Sample RSS Feed for the News module CGFeedMaker 1.0.16 on CMS Made Simple fdiallo@human-connect.com (fred ) Chemical Tuning Enhances Both Potency Towards Nrf2 and In Vitro Therapeutic Index of Triterpenoids http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=38&cntnt01returnid=58 Tue, 12 Apr 2016 18:15:06 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=38&cntnt01returnid=58 Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity-implications for therapeutic targeting of Nrf2. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=37&cntnt01returnid=58 Tue, 12 Apr 2016 18:10:51 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=37&cntnt01returnid=58 Comparative Proteomic Characterization of 4 Human Liver-Derived Single Cell Culture Models Reveals Significant Variation in the Capacity for Drug Disposition, Bioactivation, and Detoxication. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=36&cntnt01returnid=58 Tue, 12 Apr 2016 18:09:36 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=36&cntnt01returnid=58 Cellular Accumulation and Toxic Effects of Bile Acids in Cyclosporine A-Treated HepaRG Hepatocytes. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=35&cntnt01returnid=58 Tue, 12 Apr 2016 18:08:00 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=35&cntnt01returnid=58 Comparative Localization and Functional Activity of the Main Hepatobiliary Transporters in HepaRG Cells and Primary Human Hepatocytes. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=34&cntnt01returnid=58 Tue, 12 Apr 2016 18:05:58 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=34&cntnt01returnid=58 Activation of the Nrf2 response by intrinsic hepatotoxic drugs correlates with suppression of NF-κB activation and sensitizes toward TNFα-induced cytotoxicity. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=33&cntnt01returnid=58 Tue, 12 Apr 2016 18:04:25 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=33&cntnt01returnid=58 High Content Analysis of Human Pluripotent Stem Cell Derived Hepatocytes Reveals Drug Induced Steatosis and Phospholipidosis. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=32&cntnt01returnid=58 Tue, 12 Apr 2016 18:02:07 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=32&cntnt01returnid=58 One Standardized Differentiation Procedure Robustly Generates Homogenous Hepatocyte Cultures Displaying Metabolic Diversity from a Large Panel of Human Pluripotent Stem Cells. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=31&cntnt01returnid=58 Tue, 12 Apr 2016 17:51:52 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=31&cntnt01returnid=58 Quantitative high content imaging of cellular adaptive stress response pathways in toxicity for chemical safety assessment. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=30&cntnt01returnid=58 Tue, 12 Apr 2016 17:49:07 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=30&cntnt01returnid=58 A 3D in vitro model of differentiated HepG2 cell spheroids with improved liver-like properties for repeated dose high-throughput toxicity studies. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=29&cntnt01returnid=58 Tue, 12 Apr 2016 17:47:02 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=29&cntnt01returnid=58 Drug-induced endoplasmic reticulum and oxidative stress responses independently sensitize toward TNFα-mediated hepatotoxicity. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=28&cntnt01returnid=58 Tue, 12 Apr 2016 17:40:02 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=28&cntnt01returnid=58 MIP-DILI poster http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=27&cntnt01returnid=58 Tue, 07 Oct 2014 11:14:47 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=27&cntnt01returnid=58 MIP-DILI overview http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=26&cntnt01returnid=58 Tue, 07 Oct 2014 10:35:37 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=26&cntnt01returnid=58 Impact of Inflammation on Chlorpromazine-induced Cytotoxicity and Cholestatic Features in HepaRG Cells. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=25&cntnt01returnid=58 Fri, 25 Jul 2014 10:35:11 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=25&cntnt01returnid=58 Different Dose-Dependent Mechanisms are Involved in Early Cyclosporine A-Induced Cholestatic Effects in HepaRG Cells. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=24&cntnt01returnid=58 Fri, 25 Jul 2014 10:32:27 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=24&cntnt01returnid=58 PPAR agonists reduce steatosis in oleic acid-overloaded HepaRG cells. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=23&cntnt01returnid=58 Fri, 25 Jul 2014 10:18:45 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=23&cntnt01returnid=58 EUROTOX 2014 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=22&cntnt01returnid=58 Wed, 23 Jul 2014 11:01:33 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=22&cntnt01returnid=58 Effect of human glutathione s-transferases on glutathione-dependent inactivation of cytochrome p450-dependent reactive intermediates of diclofenac. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=21&cntnt01returnid=58 Tue, 03 Dec 2013 15:14:18 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=21&cntnt01returnid=58 Ontogeny, distribution and potential roles of 5-hydroxymethylcytosine in human liver function. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=20&cntnt01returnid=58 Tue, 03 Dec 2013 15:13:19 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=20&cntnt01returnid=58 In-solution hybrid capture of bisulfite-converted DNA for targeted bisulfite sequencing of 174 ADME genes. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=19&cntnt01returnid=58 Tue, 03 Dec 2013 15:12:35 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=19&cntnt01returnid=58 Characterization of human cytochrome P450s involved in the bioactivation of clozapine. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=18&cntnt01returnid=58 Tue, 03 Dec 2013 15:11:02 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=18&cntnt01returnid=58 Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects. http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=17&cntnt01returnid=58 Tue, 03 Dec 2013 15:08:11 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=17&cntnt01returnid=58 2nd MIP-DILI Annual Meeting http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=16&cntnt01returnid=58 Tue, 03 Dec 2013 15:05:35 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=16&cntnt01returnid=58 Workshop III http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=15&cntnt01returnid=58 Tue, 03 Dec 2013 15:03:52 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=15&cntnt01returnid=58 Issue 2, November 2013 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=14&cntnt01returnid=58 Fri, 29 Nov 2013 15:52:49 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=14&cntnt01returnid=58 Issue 1, July 2013 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=13&cntnt01returnid=58 Wed, 31 Jul 2013 15:14:02 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=13&cntnt01returnid=58 Event 2013: 1st MIP-DILI Annual Meeting http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=12&cntnt01returnid=58 Tue, 29 Jan 2013 14:55:15 +0100 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=12&cntnt01returnid=58 Overtaking the DILI Model http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=8&cntnt01returnid=58 Tue, 02 Oct 2012 10:34:20 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=8&cntnt01returnid=58 MIP-DILI press release IMI JU http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=6&cntnt01returnid=58 Tue, 02 Oct 2012 09:24:02 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=6&cntnt01returnid=58 Drugs that are kinder to the liver http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=4&cntnt01returnid=58 Mon, 01 Oct 2012 17:27:09 +0200 http://www.mipdili.eu/index.php?mact=News,cntnt01,detail,0&cntnt01articleid=4&cntnt01returnid=58